Age-Related Changes in Antioxidative Enzyme Capacity in Tongue of Fischer 344 Rats

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Age-Related Changes in Antioxidative Enzyme Capacity in Tongue of Fischer 344 Rats

OBJECTIVES Antioxidative enzyme efficiency changes in some organs with age. However, no study has been conducted on age-related antioxidant enzyme changes in tongue. In the present study, the authors investigated the activities of four antioxidative enzymes and their protein expressions in the tongues of young and old Fischer 344 rats. METHODS Age-dependent changes in the enzyme activities of...

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Age-related changes in cardiac structure and function in Fischer 344 Brown Norway hybrid rats

Hacker, Timothy A., Susan H. McKiernan, Pamela S. Douglas, Jonathan Wanagat, and Judd M. Aiken. Age-related changes in cardiac structure and function in Fischer 344 Brown Norway hybrid rats. Am J Physiol Heart Circ Physiol 290: H304–H311, 2006. First published September 2, 2005; doi:10.1152/ajpheart.00290.2005.— The effects of aging on cardiovascular function and cardiac structure were determin...

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Age-related changes in cardiac structure and function in Fischer 344 x Brown Norway hybrid rats.

The effects of aging on cardiovascular function and cardiac structure were determined in a rat model recommended for gerontological studies. A cross-sectional analysis assessed cardiac changes in male Fischer 344 x Brown Norway F1 hybrid rats (FBN) from adulthood to the very aged (n = 6 per 12-, 18-, 21-, 24-, 27-, 30-, 33-, 36-, and 39-mo-old group). Rats underwent echocardiographic and hemody...

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Age-related and light-associated retinal changes in Fischer rats.

Morphological changes in retinas of aging Fischer 344 rats were characterized. The numbers of photoreceptor cells gradually decreased as rats aged. The outer nuclear layer was 12 cells thick at 3 months, but was reduced to less than 8 cells by 18 months. The decrease of photoreceptor cells was more pronounced in rats housed under a light intensity of 32-ft-c than in rats housed under a light in...

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Age-associated changes in hearts of male Fischer 344/Brown Norway F1 rats.

Aging is associated with left ventricular hypertrophy, dilatation, and fibrosis of the heart. The Fischer 344/Brown Norway F1 (F344/BNF1) rat is recommended for age-related studies by the National Institutes on Aging because this hybrid rat lives longer and has a lower rate of pathological conditions than inbred rats. However, little is known about age-associated changes in cardiac and aortic f...

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ژورنال

عنوان ژورنال: Clinical and Experimental Otorhinolaryngology

سال: 2016

ISSN: 1976-8710,2005-0720

DOI: 10.21053/ceo.2015.01648